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Admin11.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

5 Department of Medical Oncology, West German Cancer Centre, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Admin02.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

The median was used to set a cut-off between high and low gene expression Srinivasan G, Sidhu GS, Williamson EA, Jaiswal AS, Najmunnisa N, Wilcoxen K, Jones D, George TJ Jr, Hromas R.
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Admin01.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Therefore, 91 clinical MPM samples were digitally screened for gene expression patterns of HR members.
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Admin07.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

1 Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
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Admin25.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Threshold was set at 600 counts.
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Admin01.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Borchert S, Suckrau PM, Walter RFH, Wessolly M, Mairinger E, Steinborn J, Hegedus B, Hager T, Herold T, Eberhardt WEE, Wohlschlaeger J, Aigner C, Bankfalvi A, Schmid KW, Mairinger FD.
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Admin19.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Results: A BRCAness-dependent increase of apoptosis and senescence during olaparib-based treatment of BRCA-associated-protein 1 BAP1 -mutated cell lines was observed.
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Admin01.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Competing interests All authors have read and approved the manuscript and are aware of the submission.
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Admin15.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Turkcu G, AlabalIk U, Keles AN, Ibiloglu I, Kucukoner M, Sen HS, et al.
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Admin23.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Low expression is highlighted in red, high expression is highlighted in green.
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Admin02.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

The authors declare no conflict of interest.
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Admin24.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

PMID: 33122816 Free PMC article.
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